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NADA
Rapid Sampling, Pooling and Targeted Deep Sequencing for Effective Malaria Molecular Surveillance
NMIMR_POOLING
Prof Anita Ghansah
Brown university
Bailey lab
Noguchi Memorial Institute for Medical Research
NADA
Bill and Melinda Gates foundation
Prof Anita Ghansah
v1
Ghana
Ada East, Dzodze, Ejura, Kade, Kenyasi, Nkoransa, Walewale, Weija, Zebilla
Individual/Facility level
sample survey data[ssd]
The “Pooling Project” is an innovative malaria molecular surveillance (MMS) system which combines sampling, pooling and next generation sequencing to effectively monitor antimalarial resistance at a reduced cost. This project is a collaborative effort between the Noguchi memorial institute for medical research (NMIMR), the Ghana National malaria elimination program (NMEP) and supported by the Bailey lab-Brown University. The aim of the project is to ultimately provide near real-time access to actionable molecular surveillance data to improve the MMS system of Ghana.
This is done through the rapid collection of blood samples from malaria patients by clinical staff as a preserved liquid sample followed by laboratory pooling, and next-generation sequencing. Ten NMEP sites are currently involved in this study and genotyping of samples is done in NMIMR with support from collaborators in Brown university, Bailey lab.
Funding for this project is from the Bill and Melinda Gates foundation.
A computer-assisted personal interviewing (CAPI) and Laboratory Work
Survey data was collected using Tablets enterd in REDCap Mobile Application.
Prof Anita Ghansah